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The Cas9 protein (CRISPR-associated protein 9), derived from type II CRISPR(clusteredregularly,interspaced,short,palindromic,repeats),bacterial,immune,systems,is,becoming anessential tool for engineering the genome in diverse organisms. As anRNAguidedDNAendonuclease,Cas9,is,designatedtotarget,new,sites,by,altering,its,guide,RNA,sequence,and,its,development,as,a,tool,has,madesequencespecific,gene,editing,much,easier.The,nucleasedeactivated,form,of,dCas9,further,provides,a,versatile,RNA,guided,DNAtargeting,platform,for regulating and imaging the genome in nucleus, as well as for rewriting the epigenetic dynamics, all in a sequence-specific manner. With all of these progress, scientists have begun to explore the possible applications of Cas9 in biomedical research and therapeutics. Novatein Biosciences is working hard to help you in fully utilize the Cas9 related proteins, antibodies, and assay kit to advance your projects. We focus on the applications of Cas9 proteins for genome editing, regulation, and subcellular localization of target genes.
Cas9蛋白(CRISPR相关蛋白9)来源于II型CRISPR(聚集的规则间隔的短回文重复序列)细菌免疫系统,正成为在多种生物中构建基因组的重要工具。Cas9作为一种RNA引导的DNA内切酶,通过改变其引导RNA序列来定位新的位点,其作为一种工具的发展使序列特异性基因编辑变得更加容易。核酸酶失活形式的dCas9进一步提供了一个多功能的RNA引导的DNA靶向平台,用于调控和成像细胞核中的基因组,以及重写表观遗传动力学,所有这些都是以序列特异的方式进行的。随着这些进展,科学家们开始探索Cas9在生物医学研究和治疗学中的可能应用。Novatein Biosciences正在努力帮助您充分利用Cas9相关的蛋白质、抗体和检测试剂盒来推进您的项目。我们重点研究Cas9蛋白在基因组编辑、调控和靶基因亚细胞定位中的应用。
Cas9蛋白产品系列一:
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